2022
Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate.
Koberstein JN, Stewart ML, Smith CB, Tarasov AI, Ashcroft FM, Stork PJS, Goodman RH. Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate. Proc Natl Acad Sci U S A 2022, 119: e2204407119. PMID: 35881794, DOI: 10.1073/pnas.2204407119.Peer-Reviewed Original Research
2016
Biosensor reveals multiple sources for mitochondrial NAD⁺.
Cambronne XA, Stewart ML, Kim D, Jones-Brunette AM, Morgan RK, Farrens DL, Cohen MS, Goodman RH. Biosensor reveals multiple sources for mitochondrial NAD⁺. Science (New York, N.Y.) 2016, 352: 1474-7. PMID: 27313049, PMCID: PMC6530784, DOI: 10.1126/science.aad5168.Peer-Reviewed Original Research
2004
Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions.
Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM, Yochum GS, Boss JM, McWeeney S, Dunn JJ, Mandel G, Goodman RH. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell 2004, 119: 1041-54. PMID: 15620361, DOI: 10.1016/j.cell.2004.10.032.Peer-Reviewed Original Research
2002
Regulation of corepressor function by nuclear NADH.
Zhang Q, Piston DW, Goodman RH. Regulation of corepressor function by nuclear NADH. Science 2002, 295: 1895-7. PMID: 11847309, DOI: 10.1126/science.1069300.Peer-Reviewed Original Research
1995
Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.
Lundblad JR, Kwok RP, Laurance ME, Harter ML, Goodman RH. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature 1995, 374: 85-8. PMID: 7870179, DOI: 10.1038/374085a0.Peer-Reviewed Original Research
1994
Nuclear protein CBP is a coactivator for the transcription factor CREB.
Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bächinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 1994, 370: 223-6. PMID: 7913207, DOI: 10.1038/370223a0.Peer-Reviewed Original Research
1993
Phosphorylated CREB binds specifically to the nuclear protein CBP.
Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 1993, 365: 855-9. PMID: 8413673, DOI: 10.1038/365855a0.Peer-Reviewed Original Research
1986
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.
Montminy M, Sevarino K, Wagner J, Mandel G, Goodman R. Identification of a cyclic-AMP-responsive element within the rat somatostatin gene. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 6682-6686. PMID: 2875459, PMCID: PMC386573, DOI: 10.1073/pnas.83.18.6682.Peer-Reviewed Original ResearchConceptsRat somatostatin geneSomatostatin geneCAMP responsivenessReporter gene encoding chloramphenicolTranscriptional initiation siteProtein kinase 2Promoter deletion mutantsSimian virus 40 promoterSomatostatin gene promoterCAMP-responsive elementPC12 rat pheochromocytoma cellsKinase 2 activityGene encoding chloramphenicolTranscriptional regulationDeletion mutantsChimeric genePromoter elementsGene promoterGene expressionKinase 2Rat pheochromocytoma cellsInitiation siteResponsive elementGenesBase pairs
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