2023
Predictive Value of CT Biomarkers in Lung Transplantation Survival: Preliminary Investigation in a Diverse, Underserved, Urban Population
Friedman R, Tarasova A, Jain V, Ye K, Mansour A, Haramati L. Predictive Value of CT Biomarkers in Lung Transplantation Survival: Preliminary Investigation in a Diverse, Underserved, Urban Population. Lung 2023, 201: 581-590. PMID: 37917190, DOI: 10.1007/s00408-023-00650-6.Peer-Reviewed Original ResearchConceptsCT biomarkersPredictive valueHounsfield unitsFat areaErector spinaeSingle-center retrospective cohort studyHigh visceral fat areaDonor lung availabilityLung transplant programsLung transplant survivalLung transplantation survivalResultsThe study cohortRetrospective cohort studyPost-transplant survivalVertebral body Hounsfield unitsVisceral fat areaKaplan-Meier curvesSubcutaneous fat areaAbsence of sarcopeniaMuscle areaCox proportional hazardsPectoralis muscle areaLung transplantCohort studyStudy cohortBend but don't break: Experience of a diverse New York City lung cancer screening program during the first year of the COVID-19 pandemic
Stahl M, Shamah S, Wattamwar K, Furlani A, Serrano M, Haramati L. Bend but don't break: Experience of a diverse New York City lung cancer screening program during the first year of the COVID-19 pandemic. Clinical Imaging 2023, 100: 1-6. PMID: 37120922, PMCID: PMC10129344, DOI: 10.1016/j.clinimag.2023.04.011.Peer-Reviewed Original ResearchConceptsCancer screening programsLung cancer screening programsScreening programLung cancerPre-pandemic periodCOVID-19 pandemicLung-RADS scorePercentage of examsPandemic periodFirst yearRetrospective cohortAppropriate followPandemic surgeScreening volumeHigh mortalityPatientsCOVID surgeNew York StateCancerCOVID-19Significant differencesDemographic subgroupsCohortFollowInner-city programLung Cancer Screening Penetration in an Urban Underserved County
Lee K, Haramati L, Ye K, Lin J, Mardakhaev E, Gohari A. Lung Cancer Screening Penetration in an Urban Underserved County. Lung 2023, 201: 243-249. PMID: 36892635, DOI: 10.1007/s00408-023-00609-7.Peer-Reviewed Original ResearchConceptsLung cancer screening programsCancer screening programsRace/ethnicityLung cancerScreening programSocioeconomic statusMethodsThis retrospective cohort studyRetrospective cohort studyInstitutional review board approvalLung cancer screeningUrban medical centerReview board approvalSignificant differencesTwo-sample t-testLower SES neighborhoodsCohort studyMore patientsHispanic patientsCancer screeningCancer cohortUnderserved countiesInclusion criteriaMedical CenterBoard approvalPatients
2022
Using Routine Chest Computed Tomography to Diagnose Pulmonary Embolism
Chan J, Ho B, Ye K, Haramati L, Jain V. Using Routine Chest Computed Tomography to Diagnose Pulmonary Embolism. Journal Of Computer Assisted Tomography 2022, 46: 888-893. PMID: 36399535, DOI: 10.1097/rct.0000000000001372.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansLungMaleMiddle AgedPulmonary ArteryPulmonary EmbolismThoraxTomography, X-Ray ComputedConceptsPulmonary embolismPulmonary artery enhancementContrast-enhanced chest CT scansHU thresholdContrast-enhanced chest CTAbsence of PEUnsuspected pulmonary embolismContrast-enhanced chestHounsfield unitsChest CT scanLogistic regression analysisPeripheral enhancementPulmonary vasculatureChest CTFemale sexRoutine chestContrast amountCT scanPulmonary enhancementTotal casesOlder ageEmbolismRegression analysisChestDescriptive statisticsCOVID-19 in Kidney Transplant Recipient and Waitlist Patients
Dong Y, Dhingra A, Shamir S, Azzi Y, Ye K, Greenstein S, Haramati L. COVID-19 in Kidney Transplant Recipient and Waitlist Patients. Journal Of Thoracic Imaging 2022, 37: 133-139. PMID: 35439238, PMCID: PMC9018208, DOI: 10.1097/rti.0000000000000640.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsTransplant recipientsICU admissionHospital admissionSecondary outcomesWaitlist patientsIntensive care unit admissionCoronavirus disease 2019 (COVID-19) patientsCOVID-19Care unit admissionKidney transplant patientsPatient's chest radiographReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionMultivariate regression analysisRadiographic severity scoreUnit admissionTransplant patientsRetrospective cohortPrimary outcomeSeverity scoreTransplant waitlistWorse outcomesChest radiographsPatients
2021
Clearing the Congestion
Berman J, Lee L, Monga R, Ye K, Sprayregen S, Haramati L. Clearing the Congestion. Journal Of Thoracic Imaging 2021, 38: 18-22. PMID: 34739426, DOI: 10.1097/rti.0000000000000625.Peer-Reviewed Original ResearchConceptsNormal brain natriuretic peptideBrain natriuretic peptideCongestive heart failureHistory of CHFSerum brain natriuretic peptideHigher body mass indexBody mass indexBNP levelsMass indexPresence of CHFHigher serum BNP levelsSerum BNP levelsEmergency department patientsED cohortCXR resultsHeart failureDepartment patientsED patientsStudy cohortNatriuretic peptideClinical dilemmaChest radiographsPatientsCXRLogistic regressionA Retrospective Multi-Site Academic Center Analysis of Pneumothorax and Associated Risk Factors after CT-Guided Percutaneous Lung Biopsy
Rong E, Hirschl D, Zalta B, Shmukler A, Krausz S, Levsky J, Lin J, Haramati L, Gohari A. A Retrospective Multi-Site Academic Center Analysis of Pneumothorax and Associated Risk Factors after CT-Guided Percutaneous Lung Biopsy. Lung 2021, 199: 299-305. PMID: 33876295, DOI: 10.1007/s00408-021-00445-7.Peer-Reviewed Original ResearchConceptsChest tube placementLung biopsyPneumothorax riskTube placementRisk factorsSmaller lesion sizeLung surgeryLesion sizeSubcutaneous tissueCT-guided lung biopsyPercutaneous lung biopsyFrequency of complicationsAssociated risk factorsChest X-rayImmediate pneumothoraxSmoking historyDelayed pneumothoraxLung cancerChest radiographsWall biopsyPneumothoraxPatientsBiopsyBiopsy techniqueCenter analysis
2020
Utility of Apical Lung Assessment on Computed Tomography Angiography as a COVID-19 Screen in Acute Stroke
Esenwa C, Lee J, Nisar T, Shmukler A, Goldman I, Zampolin R, Hsu K, Labovitz D, Altschul D, Haramati L. Utility of Apical Lung Assessment on Computed Tomography Angiography as a COVID-19 Screen in Acute Stroke. Stroke 2020, 51: 3765-3769. PMID: 33115325, PMCID: PMC7678646, DOI: 10.1161/strokeaha.120.030959.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeComputed tomography angiographyLung assessmentTomography angiographyPredictive valuePatient-reported symptomsShortness of breathCoronavirus disease 2019Self-reported clinical symptomsCOVID-19Negative predictive valuePositive predictive valueAccurate screening toolAcute strokeIschemic strokeLung findingsClinical symptomsLung apexDisease 2019Lung examAngiographyDiagnostic accuracyScreening toolPatientsSymptomsThoracic aortic dissection classification among radiologists and surgeons and management trends
Grant J, Allen A, Traube L, Levsky J, Haramati L. Thoracic aortic dissection classification among radiologists and surgeons and management trends. Emergency Radiology 2020, 28: 297-301. PMID: 33025220, DOI: 10.1007/s10140-020-01861-7.Peer-Reviewed Original ResearchConceptsIntramural hematomaAortic dissectionDiscrepancy rateMean age 60Stanford type AElectronic health recordsB dissectionMedical managementStanford classificationPatient managementAge 60B classificationDissectionHealth recordsSurgeonsRadiology reportsType ARadiologistsCTHematomaObjectiveToManagementResultsNewlyDiagnostic Performance of Pulmonary Embolism Imaging in Patients with History of Asthma.
Lazarus M, Kim Y, Mathai B, Levsky J, Freeman L, Haramati L, Moadel R. Diagnostic Performance of Pulmonary Embolism Imaging in Patients with History of Asthma. Journal Of Nuclear Medicine 2020, 62: 399-404. PMID: 32680927, DOI: 10.2967/jnumed.120.242776.Peer-Reviewed Original ResearchConceptsHistory of asthmaPulmonary embolismFalse negative rateRepeat examsDiagnostic performanceChronic lung diseaseVentilation-perfusion scanningHigh false-negative rateLung diseaseCT pulmonaryNegative imagingNondiagnostic resultsVentilation defectsAsthmaCTPANegative casesEmbolismPatientsHigh rateAdultsExamPulmonaryHistorySymptomsDiseaseImplementation of an aortic dissection CT protocol with clinical decision support aimed at decreasing radiation exposure by reducing routine abdominopelvic imaging
Patel V, Fruauff A, Esses D, Lipsitz E, Levsky J, Haramati L. Implementation of an aortic dissection CT protocol with clinical decision support aimed at decreasing radiation exposure by reducing routine abdominopelvic imaging. Clinical Imaging 2020, 67: 108-112. PMID: 32559680, DOI: 10.1016/j.clinimag.2020.06.005.Peer-Reviewed Original ResearchConceptsAcute aortic syndromeAortic dissectionAortic syndromeClinical decision supportED patientsChest/abdomen/pelvisRadiation doseDiagnostic accuracyStudy periodTotal ED populationMedian radiation doseAbdomen/pelvisRoutine abdominopelvicVs. 3.7ED populationContrast doseDiagnostic yieldRetrospective analysisCT scanCT protocolPatientsDissectionRadiation exposureDoseScreening protocolCT Scans Obtained for Nonpulmonary Indications: Associated Respiratory Findings of COVID-19
Hossain R, Lazarus M, Roudenko A, Dako F, Mehta V, Alis J, Zalta B, Lei B, Haramati L, White C. CT Scans Obtained for Nonpulmonary Indications: Associated Respiratory Findings of COVID-19. Radiology 2020, 296: 201743. PMID: 32391741, PMCID: PMC7437495, DOI: 10.1148/radiol.2020201743.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBetacoronavirusCoronavirus InfectionsCOVID-19Emergency Service, HospitalFemaleGastrointestinal DiseasesHumansIncidental FindingsLungMaleMiddle AgedPandemicsPneumonia, ViralRadiography, AbdominalRetrospective StudiesSARS-CoV-2Spinal DiseasesSpineTomography, X-Ray ComputedConceptsCoronavirus disease 2019Nonrespiratory symptomsGroup 2Emergency departmentCervical spineCT scanGroup 1CT findingsDisease 2019COVID-19COVID-19-related pneumoniaLung parenchymal findingsPulmonary COVID-19Results Group 1Group 1 patientsCommon CT findingsGround-glass opacitiesReverse transcription-polymerase chain reaction resultsFisher's exact testTranscription-polymerase chain reaction resultsCOVID-19 testingPolymerase chain reaction resultsPulmonary diseaseRT-PCR resultsAtypical manifestationsComparison Between Anatomical and Functional Imaging Modalities for Evaluation of Chest Pain in the Emergency Department
Kargoli F, Levsky J, Bulcha N, Mustehsan M, Brown-Manhertz D, Furlani A, Polanco D, Mizrachi S, Makkiya M, Golive A, Haramati L, Taub C, Garcia M. Comparison Between Anatomical and Functional Imaging Modalities for Evaluation of Chest Pain in the Emergency Department. The American Journal Of Cardiology 2020, 125: 1809-1814. PMID: 32345475, DOI: 10.1016/j.amjcard.2020.03.024.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingStress echocardiographyEmergency departmentChest painRehospitalization ratesCoronary angiographyLeast intermediate riskNegative initial troponinUrban ED settingDiagnostic coronary angiographyRetrospective cohort studyHospital emergency departmentUrban hospital emergency departmentFunctional imaging modalitiesCCTA groupInitial troponinED dischargeCohort studyIntermediate riskSecondary outcomesNondiagnostic electrocardiogramPrimary outcomeED settingTomography angiographyClinical utilityPerformance of the Vancouver Risk Calculator Compared with Lung-RADS in an Urban, Diverse Clinical Lung Cancer Screening Cohort
Kessler A, Peng R, Mardakhaev E, Haramati L, White C. Performance of the Vancouver Risk Calculator Compared with Lung-RADS in an Urban, Diverse Clinical Lung Cancer Screening Cohort. Radiology Imaging Cancer 2020, 2: e190021. PMID: 33778703, PMCID: PMC7983652, DOI: 10.1148/rycan.2020190021.Peer-Reviewed Original ResearchConceptsLung CT Screening ReportingLung-RADSFalse-negative findingsRadiology's Lung CT Screening ReportingLung cancer screening cohortAccountability Act-compliant retrospective studyLung cancer screening programsLung-RADS scoreInstitutional review board approvalCancer screening programsLung nodulesLung cancer screeningRisk of cancerReview board approvalDiverse clinical settingsMean followScreening cohortRetrospective studyRisk calculatorCancer screeningLung cancerScreening programStudy populationLung cancer detectionAmerican College
2019
The relationship between adrenal incidentalomas and mortality risk
Taya M, Paroder V, Bellin E, Haramati L. The relationship between adrenal incidentalomas and mortality risk. European Radiology 2019, 29: 6245-6255. PMID: 30993434, PMCID: PMC6801004, DOI: 10.1007/s00330-019-06202-y.Peer-Reviewed Original ResearchConceptsAdrenal incidentalomasMortality riskSurvival analysisNational Death Index queryCox proportional hazards modelAdrenal incidentaloma patientsMethodsRetrospective cohort studyPeripheral vascular diseaseChronic pulmonary diseaseCause mortality riskIncidence of malignancyKaplan-Meier curvesEmergency room presentationProportional hazards modelAcademic medical centerAbdominal CT examsIncidentaloma patientsCause mortalityHospital deathCohort studyAdrenal diseaseCT abdomenHeart failurePulmonary diseaseRenal diseaseVancouver Risk Calculator Compared with ACR Lung-RADS in Predicting Malignancy: Analysis of the National Lung Screening Trial
White C, Dharaiya E, Dalal S, Chen R, Haramati L. Vancouver Risk Calculator Compared with ACR Lung-RADS in Predicting Malignancy: Analysis of the National Lung Screening Trial. Radiology 2019, 291: 205-211. PMID: 30667335, DOI: 10.1148/radiol.2018181050.Peer-Reviewed Original ResearchConceptsNational Lung Screening TrialLung-RADSLung Imaging ReportingPatient basisRisk calculatorScreening TrialImaging ReportingRadiology Lung Imaging ReportingRisk of malignancyAmerican CollegeSolid nodulesSubsolid nodulesNodule basisMalignancyTotal nodulesNodulesData SystemTrialsSpecificityPatientsReporting
2018
Effectiveness of Lung-RADS in Reducing False-Positive Results in a Diverse, Underserved, Urban Lung Cancer Screening Cohort
Kaminetzky M, Milch H, Shmukler A, Kessler A, Peng R, Mardakhaev E, Bellin E, Levsky J, Haramati L. Effectiveness of Lung-RADS in Reducing False-Positive Results in a Diverse, Underserved, Urban Lung Cancer Screening Cohort. Journal Of The American College Of Radiology 2018, 16: 419-426. PMID: 30146484, DOI: 10.1016/j.jacr.2018.07.011.Peer-Reviewed Original ResearchConceptsLung cancer screening cohortNational Lung Screening TrialPercent of patientsNational Death IndexLung cancer screeningLung-RADSLung cancer ratesCancer ratesScreening cohortDeath IndexCancer screeningLung cancerScreening TrialCT resultsLung CT Screening ReportingFirst annual examinationLung cancer prevalenceLung-RADS 1Lung-RADS 2Lung-RADS 3Institutional review board approvalLung-RADS categoriesClinical screening programReview board approvalUnderserved urban populationVentricular Myocardial Fat: An Unexpected Biomarker for Long-term Survival?
Bader AS, Levsky JM, Zalta BA, Shmukler A, Gohari A, Jain VR, Chernyak V, Lovihayeem M, Bellin EY, Haramati LB. Ventricular Myocardial Fat: An Unexpected Biomarker for Long-term Survival? European Radiology 2018, 29: 241-250. PMID: 29948081, DOI: 10.1007/s00330-018-5546-4.Peer-Reviewed Original ResearchConceptsMyocardial fatMI groupCharlson scoreCause mortalityPrior MIRisk stratificationChest CTBetter survivalChronic myocardial infarction patientsTraditional risk prediction modelsCox proportional hazards analysisNon-contrast chest CTMethodsA retrospective cohortCardiovascular risk factorsAge-matched patientsProportional hazards analysisTraditional cardiovascular riskNet reclassification improvementMyocardial infarction patientsUrban academic centerNon-contrast CTMeaningful prognostic valueLong-term survivalRisk prediction modelAdjusted hazardCoronary Computed Tomography Angiography Versus Stress Echocardiography in Acute Chest Pain A Randomized Controlled Trial
Levsky J, Haramati L, Spevack D, Menegus M, Chen T, Mizrachi S, Brown-Manhertz D, Selesny S, Lerer R, White D, Tobin J, Taub C, Garcia M. Coronary Computed Tomography Angiography Versus Stress Echocardiography in Acute Chest Pain A Randomized Controlled Trial. JACC Cardiovascular Imaging 2018, 11: 1288-1297. PMID: 29909113, DOI: 10.1016/j.jcmg.2018.03.024.Peer-Reviewed Original ResearchMeSH KeywordsAdultAngina PectorisClinical Decision-MakingComparative Effectiveness ResearchComputed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseEchocardiography, StressEmergency Service, HospitalFemaleHumansLength of StayMaleMiddle AgedMultidetector Computed TomographyPatient AdmissionPatient SelectionPredictive Value of TestsRadiation DosageRadiation ExposureTreatment OutcomeTriageConceptsCoronary CTACardiovascular eventsHospital lengthAcute chest pain patientsMajor adverse cardiovascular eventsRadiation exposureMedian hospital lengthAdverse cardiovascular eventsMedian ED lengthChest pain patientsCoronary artery diseaseEmergency department useSerum troponin levelsChest pain triageCTA patientsPrimary endpointSafety endpointSecondary endpointsPatient ageTroponin levelsArtery diseaseED lengthPain patientsSE patientsStress echocardiographyScreening Patterns and Mortality Differences in Patients With Lung Cancer at an Urban Underserved Community
Su C, Bhargava A, Shah C, Halmos B, Gucalp R, Packer S, Ohri N, Haramati L, Perez-Soler R, Cheng H. Screening Patterns and Mortality Differences in Patients With Lung Cancer at an Urban Underserved Community. Clinical Lung Cancer 2018, 19: e767-e773. PMID: 29937386, DOI: 10.1016/j.cllc.2018.05.019.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedCarcinoma, Squamous CellCombined Modality TherapyDecision Support TechniquesEarly Detection of CancerFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMedically Underserved AreaMiddle AgedPrognosisRetrospective StudiesSmall Cell Lung CarcinomaSurvival RateTomography, X-Ray ComputedUrban PopulationConceptsUnited States Preventative Services Task Force guidelinesPrimary lung cancerTask Force guidelinesLung cancerScreening TrialMortality differencesPrimary care provider statusScreen-detected lung cancersNational Lung Screening TrialLung cancer-related mortalityLung Cancer Screening TrialActive smoking statusTime of diagnosisCancer Screening TrialCancer-related mortalityUnderserved communitiesUrban underserved communitiesLCS eligibilityCause mortalityPatient characteristicsProspective trialCurative treatmentSmoking statusSurgical managementCox regression
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