Feifei Zhang
Associate Research Scientist in GeneticsAbout
Research
Publications
2024
The White Matter Integrity and Functional Connection Differences of Fornix (Cres)/Stria Terminalis in Individuals with Mild Cognitive Impairment Induced by Occupational Aluminum Exposure
Zhang F, Li Y, Chen R, Shen P, Wang X, Meng H, Du J, Yang G, Liu B, Niu Q, Zhang H, Tan Y. The White Matter Integrity and Functional Connection Differences of Fornix (Cres)/Stria Terminalis in Individuals with Mild Cognitive Impairment Induced by Occupational Aluminum Exposure. ENeuro 2024, 11: eneuro.0128-24.2024. PMID: 39142823, PMCID: PMC11360986, DOI: 10.1523/eneuro.0128-24.2024.Peer-Reviewed Original ResearchConceptsMild cognitive impairmentFunctional connectivityCognitive impairmentNeural mechanismsRight inferior frontal gyrusResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingInferior frontal gyrusRight anterior cingulateRight temporal poleFunctional connectivity differencesWhite matter integrityRight sagittal stratumFractional anisotropy valuesAnterior cingulateFrontal gyrusDiffusion tensor imagingMontreal Cognitive AssessmentTemporal poleWhite matterWM integrityPlasma Al concentrationParacingulate gyriCognitive AssessmentSagittal stratumGenes associated with cortical thickness alterations in behavioral addiction
Xie H, Wang Y, Zhu F, Zhang F, Wu B, Zhao Z, Gan R, Gong Q, Jia Z. Genes associated with cortical thickness alterations in behavioral addiction. Cerebral Cortex 2024, 34: bhae298. PMID: 39051658, DOI: 10.1093/cercor/bhae298.Peer-Reviewed Original ResearchConceptsBehavioral addictionsCortical thicknessBehavioral regulationPostcentral gyrusCompulsive reward-seeking behaviorReward-seeking behaviorDorsolateral prefrontal cortexDopamine D2 receptorsAllen Human Brain AtlasOrbital-frontal cortexCortical thickness alterationsHuman Brain AtlasAddiction phenotypesAddiction severityPrefrontal cortexD2 receptorsDopamine metabolismBrain areasNeurogenetic mechanismsAddictionThickness alterationsPrecuneusGyrusDopamineResponse to stimuliBody Satisfaction, Exercise Dependence, and White Matter Microstructure in Young Adults
Xie H, Zhang F, Gan S, Wu J, Wu B, Qin K, Wang S, Sweeney J, Gong Q, Jia Z. Body Satisfaction, Exercise Dependence, and White Matter Microstructure in Young Adults. Journal Of Magnetic Resonance Imaging 2024, 61: 749-755. PMID: 38874990, DOI: 10.1002/jmri.29485.Peer-Reviewed Original ResearchExercise Dependence ScaleTract-based spatial statisticsWhite matter microstructureEDS scoresExercise dependenceBody shape satisfactionNeuropsychological mechanismsRight cingulumFA valuesWhole-brain tract-based spatial statisticsFractional anisotropyBody satisfactionLeft inferior frontal-occipital fasciculusQuantitative anisotropyInferior frontal occipital fasciculusFrontal-subcorticalBilateral corticospinal tractsNeural signaturesSuperior thalamic radiationSensorimotor networkDependence ScaleThalamic radiationCorrelational tractographyTractography analysisQA valuesDecoupling of gray and white matter functional networks in cognitive impairment induced by occupational aluminum exposure
Zhang F, Li L, Liu B, Shao Y, Tan Y, Niu Q, Zhang H. Decoupling of gray and white matter functional networks in cognitive impairment induced by occupational aluminum exposure. NeuroToxicology 2024, 103: 1-8. PMID: 38777096, DOI: 10.1016/j.neuro.2024.05.001.Peer-Reviewed Original ResearchExecutive control networkFunctional connectivityCognitive impairmentCognitive functionTrail Making Test Part AResting-state functional magnetic resonance imagingFunctional magnetic resonance imagingControl networkDecreased FCsReduced functional connectivityGray matterHuman cognitive functionsCognitive impairment groupExecutive controlNeurobiological mechanismsLimbic networkMontreal Cognitive AssessmentWhite matterCognitive AssessmentImpairment groupFunctional networksMagnetic resonance imagingImpairmentPart ACognitionDisrupted small-world white matter networks in patients with major depression and recent suicide plans or attempts
Li H, Zhang H, Qin K, Yin L, Chen Z, Zhang F, Wu B, Chen T, Sweeney J, Gong Q, Jia Z. Disrupted small-world white matter networks in patients with major depression and recent suicide plans or attempts. Brain Imaging And Behavior 2024, 18: 741-752. PMID: 38407738, DOI: 10.1007/s11682-024-00870-1.Peer-Reviewed Original ResearchNon-suicidal depressed patientsSuicidal depressed patientsDepressed patientsSuicide planNodal efficiencyHealthy controlsMedial orbitofrontal cortexWhite matter structural networksDecreased nodal efficiencyProximal risk factorsWhite matter networksGraph theory analysisOrbitofrontal cortexSuicide brainDiffusion tensor imagingRolandic operculumOlfactory cortexStructural networkNodal network propertiesMotor areaDeterministic tractographySuicideLocal efficiencyTensor imagingStructural connectomeNeuropsychological insights into exercise addiction: the role of brain structure and self-efficacy in middle-older individuals
Zhang F, Shao Y, Zhang X, Zhang H, Tan Y, Yang G, Wang X, Jia Z, Gong Q, Zhang H. Neuropsychological insights into exercise addiction: the role of brain structure and self-efficacy in middle-older individuals. Cerebral Cortex 2024, 34: bhad514. PMID: 38186007, DOI: 10.1093/cercor/bhad514.Peer-Reviewed Original ResearchGray matter volumeRight inferior temporal regionMatter volumeInferior temporal regionsBrain structuresExercise addictionTemporal regionsStructural magnetic resonance imagingMagnetic resonance imagingLeft rolandic operculumSPM12 softwareDevelopment of interventionsRight hippocampusStudy populationRolandic operculumResonance imagingBehavioral assessmentPhysiological changesAddictionNeuropsychological mechanismsPsychological factorsPositive correlationNegative correlationMediation analysisIndividuals
2023
Common and distinct neural correlates of emotional processing in individuals at familial risk for major depressive disorder and bipolar disorder: A comparative meta-analysis
Qin K, Pan N, Lei D, Zhang F, Yu Y, Sweeney J, DelBello M, Gong Q. Common and distinct neural correlates of emotional processing in individuals at familial risk for major depressive disorder and bipolar disorder: A comparative meta-analysis. Journal Of Affective Disorders 2023, 348: 97-106. PMID: 38113944, PMCID: PMC10846904, DOI: 10.1016/j.jad.2023.12.030.Peer-Reviewed Original ResearchMiddle occipital gyrusMajor depressive disorderHealthy controlsFamilial riskDepressive disorderBipolar disorderAbnormal functional activationPrecise prevention strategiesActivation patternsFunctional activation patternsDistinct neural phenotypesTask-based functional magnetic resonanceEmotional processingFunctional magnetic resonanceIllness onsetBrain dysfunctionFamilial predispositionMood disordersRisk relativesParahippocampal gyrusPrevention strategiesOccipital gyrusDistinct neural correlatesNeural phenotypesFunctional activationChinese version of exercise dependence scale-revised: psychometric analysis and exploration of risk factors
Shao Y, Zhang H, Zhang X, Liang Q, Zhang H, Zhang F. Chinese version of exercise dependence scale-revised: psychometric analysis and exploration of risk factors. Frontiers In Psychology 2023, 14: 1309205. PMID: 38115976, PMCID: PMC10728468, DOI: 10.3389/fpsyg.2023.1309205.Peer-Reviewed Original ResearchMann-Whitney U testRisk factorsChinese versionExercise frequencyExercise addictionU testPotential risk factorsMean ageExercise Dependence ScaleEarly detectionAdverse effectsStudy sampleDependence ScaleExercise dependencePrimary causePresent studyPsychometric analysisRegression testBehavioral studiesPsychological aspectsTarget groupGood reliabilityFactorsHierarchical regression testsEvaluation of the default mode network using nonnegative matrix factorization in patients with cognitive impairment induced by occupational aluminum exposure
Zhang F, Liu B, Shao Y, Tan Y, Niu Q, Wang X, Zhang H. Evaluation of the default mode network using nonnegative matrix factorization in patients with cognitive impairment induced by occupational aluminum exposure. Cerebral Cortex 2023, 33: 9815-9821. PMID: 37415087, DOI: 10.1093/cercor/bhad246.Peer-Reviewed Original ResearchConceptsMild cognitive impairmentGray matter volumeDefault mode networkMatter volumePlasma Al concentrationMoCA scoresCognitive impairmentOccupational aluminium exposureMode networkRey Auditory Verbal Learning Test scoreAVLT scoresEnvironmental pathogenic factorsMontreal Cognitive AssessmentStructural covariance networksPathogenic factorsAluminum exposureMale subjectsPatientsNetwork alterationsNeurodegenerative diseasesCognitive AssessmentGroup comparisonsCovariance networksVerbal memoryNeural mechanisms