2015
Implementation of pediatric cervical spine clearance guidelines at a combined trauma center
Rosati S, Maarouf R, Wolfe L, Parrish D, Poppe M, Manners R, Brown K, Haynes J. Implementation of pediatric cervical spine clearance guidelines at a combined trauma center. Journal Of Trauma And Acute Care Surgery 2015, 78: 1117-1121. PMID: 26151510, DOI: 10.1097/ta.0000000000000643.Peer-Reviewed Original ResearchConceptsNational Emergency X-Radiography Utilization StudyGuideline implementationClearance guidelinesNational Emergency X-Radiography Utilization Study criteriaComputed tomographyCervical spine clearanceTrauma centerCare management studyAdult trauma centersSpine clearanceCT clearanceUtilization studiesCT usageCT scanLevel IVImmediate effectsGuidelinesPatientsClearanceCareCenterImplementationTomographyMonthsRadiographyHistrelin for central precocious puberty—a single surgeon experience
Rosati S, Maarouf R, Brown K, Poppe M, Parrish D, Haynes J, Lanning D. Histrelin for central precocious puberty—a single surgeon experience. Journal Of Surgical Research 2015, 198: 355-359. PMID: 25899147, DOI: 10.1016/j.jss.2015.03.071.Peer-Reviewed Original ResearchConceptsCentral precocious pubertyPrecocious pubertySurgeon experienceTreatment of central precocious pubertyTreated with monthly injectionsIdiopathic central precocious pubertyInstitutional review board approvalSingle surgeon's experienceReview board approvalHistrelin acetateHistrelin implantMonthly injectionsImplant insertionRetrospective reviewSubcutaneous implantationImplant treatmentBoard approvalHistrelinAverage ageAlternative treatmentPatient satisfactionPubertyImplantationPatientsTreatment
2013
Randomized Selection Design Trial Evaluating CD8+-Enriched Versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients With Melanoma
Dudley M, Gross C, Somerville R, Hong Y, Schaub N, Rosati S, White D, Nathan D, Restifo N, Steinberg S, Wunderlich J, Kammula U, Sherry R, Yang J, Phan G, Hughes M, Laurencot C, Rosenberg S. Randomized Selection Design Trial Evaluating CD8+-Enriched Versus Unselected Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy for Patients With Melanoma. Journal Of Clinical Oncology 2013, 31: 2152-2159. PMID: 23650429, PMCID: PMC3731980, DOI: 10.1200/jco.2012.46.6441.Peer-Reviewed Original ResearchConceptsYoung tumor-infiltrating lymphocytesTumor-infiltrating lymphocytesAdoptive cell therapyCD4(+) lymphocytesCell therapyInterleukin-2High-dose IL-2 therapyAutologous tumor-infiltrating lymphocytesHigh-dose interleukin-2Infusion tumor-infiltrating lymphocytesResponse to autologous tumorTIL infusionIL-2 therapyImmunologic end pointsInterferon-gamma secretionSubgroup of patientsPeripheral blood lymphocytesResponse to treatmentLymphodepleted patientsLymphodepleting chemotherapyTIL productsTIL therapyAutologous tumorDesign trialMetastatic melanoma
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