Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy
Gupta J, Naegele J. Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy. Epilepsy Currents 2023, 23: 268-270. PMID: 37662454, PMCID: PMC10470101, DOI: 10.1177/15357597231175010.Peer-Reviewed Original ResearchModel of epilepsyTemporal lobe epilepsyLong-term efficacySpecific synaptic connectionsAbort seizuresGraft functionMishra AHost neuronsSeizure controlLobe epilepsyIntractable epilepsySeizure activityGABAergic interneuronsMonosynaptic tracingCortical interneuronsHippocampal circuitsOptogenetic activationProlonged efficacyHost inhibitionSynaptic connectionsEpilepsySeizuresEfficacyInterneuronsClinical translationForming new connections: Advances in human stem-cell-derived interneuron therapy for treating epilepsy
Gupta J, Naegele J. Forming new connections: Advances in human stem-cell-derived interneuron therapy for treating epilepsy. Neuron 2023, 111: 758-760. PMID: 36924760, DOI: 10.1016/j.neuron.2023.02.034.Peer-Reviewed Original Research
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